OUR BEST FRIENDS

whs-logo

The Sergei Foundation

shelterpet_logo

The Animal Rescue Site

B-more Dog

aldflogo

Pinups for Pitbulls

philadoptables

TFPF_Logo

Mid Atlantic Pug Rescue

Our Pack, Inc.

Maine Coonhound Rescue

Saving Shelter Pets, Inc.

mabb

LD Logo Color

Tag: cloning

Chinese scientists clone the world’s first primate; two macaque monkeys are born

monkeys_16x9leashes1

Nearly 13 years after the cloning of a dog, the species man is emotionally closest to, Chinese scientists have announced the first successful cloning of the animal man is physically closest to — the monkey.

Using the same basic technique that created Dolly the sheep in Scotland, the world’s first cloned mammal, and Snuppy the Afghan hound in South Korea, scientists in China produced two identical clones of a macaque, reigniting concerns among some that attempts to clone man are on the horizon.

The newborns — the world’s first cloned primates — were named Zhong Zhong and Hua Hua, after a Mandarin term for the Chinese nation and people.

The two healthy baby macaques were the only ones to survive to birth out of 127 altered egg cells implanted into more than 60 surrogate mothers.

The scientists behind the project said they followed the techniques of somatic cell nuclear transfer, but made a few refinements along the way. Unlike with Dolly and Snuppy, fetal cells were used rather than adult ones

Mu-ming Poo, director of the Chinese Academy of Sciences’s Institute of Neuroscience in Shanghai, who led the work, said further refinement of their methods would lead to higher success rates, Combining the cloning with gene editing will allow researchers to create “ideal nonhuman primate models” for studying disease mechanisms and screening drugs, he said.

So in answer to the seldom asked (at least by scientists) question — why clone monkeys? — that’s your immediate answer: As fodder for laboratory experiments.

The team behind the monkey cloning acknowledges that the work raises ethical questions, but Poo said he doubted it would lead to cloning man: “I would think society and the general public and governments will not allow extension of this method from nonhuman primates to humans.”

Science magazine reports that ethicists are also concerned about the monkeys themselves. “At present, it has not been sufficiently demonstrated that there are no alternatives to using macaque monkeys for such research,” Peter Dabrock, an ethicist at Friedrich-Alexander University in Erlangen, Germany, wrote in a statement.

Using nonhuman primates for research is more accepted in China than in the West, Poo said, adding “Once we demonstrate the cloned monkey’s usefulness in curing disease, I hope [Western societies] will gradually change their minds.”

He said the group is following international guidelines for the treatment and care of their monkeys.

Scientists around the world have cloned more than 20 species since Dolly the sheep was created in 1996, including dog, cat, horses, pigs, cows, rabbits, rats and mice,

Attempts to clone primates, however, had been unsuccessful, and some experts suspected primates might be resistant to the procedure.

The Chinese team reported in the Feb. 8 edition of the journal Cell that it’s difficult, but possible. The team succeeded, after many attempts, by using modulators to switch on or off certain genes that were inhibiting embryo development.

In all, it took more than 100 egg cells — merged with donor cells and implanted into surrogates — to produce two live macaque births.

Using adult cells, they achieved 22 pregnancies in 42 surrogates. That produced two births but neither survived. When they cloned using fetal monkey cells, six pregnancies were confirmed in 21 surrogates and yielded two healthy babies.

While the scientists celebrate their achievement, animal welfare groups, including PETA, condemned it.

“Cloning is a horror show: A waste of lives, time, and money – and the suffering that such experiments cause is unimaginable,” said Dr. Julia Baines, Science Policy Adviser at PETA UK. “Because cloning has a failure rate of at least 90 per cent, these two monkeys represent misery and death on an enormous scale.”

(Photo: Qiang Sun and Mu-ming Poo/Chinese Academy of Sciences)

Chinese scientists clone dogs with heart disease — and call it an achievement

longlong

China says it has managed to join South Korea as a world leader in canine cloning — by managing to create a clone of a sick dog.

Longlong, a beagle, was born with a blood-clotting disorder, and that was just what the scientists were hoping for.

The pup is a clone of Apple, a different dog whose genome was edited to develop the disease atherosclerosis, CNN reported.

longlong1By cloning the bioengineered dog, the scientists ensured they will have a good supply of diseased dogs for experiments they say could lead to cures for the condition that causes strokes and heart disease in humans.

Longlong was created by the Beijing-based biotech company Sinogene, which is boasting about having created the world’s first dog cloned from a gene-edited donor.

With Longlong’s birth, and two more clones of the bio-engineered dog being born since then, the scientists claimed that China had matched South Korea as a leader in canine cloning technology. South Korean scientists cloned the first dog, an Afghan hound named Snuppy, in 2005.

“Dogs share the most inheritable diseases with human beings, which makes them the best disease models to study,” says Feng Chong, technical director at Sinogene.

While the pups haven’t shown any signs of cardiovascular disease yet, their cloning ensures they will get it. Experimental drugs to treat cardiovascular diseases are already being tested on them.

Longlong’s birth combined two technologies: A gene-editing tool called CRISPR with somatic cell cloning technology, the method used to clone Dolly the sheep and later, Snuppy.

Zhao Jianping, vice manager of Sinogene, says the company’s success in dog cloning is about 50%. Two surrogate dogs out of four gave birth to three cloned puppies. The other two did not get pregnant.

Scientists at Sinogene believe their work aids the future of pharmaceutical development and biomedical research and it plans to produce more cloned dogs like Longlong.

“Gene-edited dogs are very useful for pharmaceutical companies,” said Feng. “The supply falls short of the demand every year.”

(Poor little pharmaceutical companies.)

The scientists also say cloning bio-engineered dogs to create puppy clones that will be born with the disease is kinder than the previous method of creating atherosclerosis in lab dogs — namely, force feeding with meals high in sugar.

Scientists, in case you haven’t noticed, have also invented a way to justify just about anything they want to do.

So if you want to hail this as a great achievement in technology, go ahead. I prefer to see it as scientists taking another giant stride toward playing God — giveth-ing life to dogs, only to taketh it away. Mankind may benefit (or at least live a longlong time), but rest assured the biggest gains will go to pharmaceutical companies.

(Photos: CNN)

South Korean university announces that Snuppy has been recloned

reclonedsnuppy

The world’s first canine clone — an Afghan hound named Snuppy who died in 2015 — has been recloned, scientists at Seoul National University in Korea have announced.

It’s no big surprise, and it’s no huge achievement, but the scientists say they created the three clones of Snuppy to “immortalize” the “milestone” Snuppy represented — and that the clones will allow them to further study the lifespan of cloned dogs.

Snuppy, who spent most of his life in a laboratory, died at age 10 in April 2015.

“Three healthy reclones of Snuppy are alive, and as with Snuppy we do not anticipate that the reclones will go through an accelerated rate of aging or will be more prone to develop diseases than naturally bred animals,” the team wrote in Scientific Reports, a journal from the publishers of Nature.

To create the new clones, the scientists used fat-derived stem cells taken from Snuppy when he was five years old.

The stem cells were taken from his belly fat and frozen. Years later, they were thawed, grown in culture and then injected into enucleated eggs taken from female donors. The reconstituted eggs were then zapped with an electrical shock to fuse the membranes of the egg and stem cells. Ninety-four of them were transferred to surrogate female dogs.

Four resulted in births, but one of the pups died four days after it was born from severe diarrhea, the scientists reported.

The three remaining dogs will also live their lives in the lab, being monitored and undergoing tests the scientist say they suspect will dispel the notion that cloned animals die early deaths.

They say the second generation of Snuppy clones will contribute to a “new era” in the study of the health and longevity of cloned animals, and that they might contribute to cures being found for human diseases.

But with dog cloning having become big business — and having been initially researched with profits in mind — it’s no surprise that the latest research, funded in part by the Korean government, aims to dispel the thinking that clones live abbreviated lives.

Snuppy’s birth came eight years after Dolly the sheep became the first cloned mammal in 1997. Dolly died prematurely, at age six.

Snuppy

Snuppy

When Snuppy was born in 2005, Time magazine named him one of the most amazing inventions of the year. What wasn’t reported much, at least not initially, were the intrusive procedures involved, the birth defects that resulted, the surplus dogs that resulted, and the long list of animal welfare concerns about the process.

In the article written in Scientific Reports, by the researchers involved, those concerns also get short shrift.

“Animal cloning has gained popularity as a method to produce genetically identical animals or superior animals for research or industrial uses,” they write.

“There is lots of pet cloning going on right now. Owners are concerned whether their clones will live (a normal lifespan) or if they will experience accelerated aging and die early. So, there is some business concern,” said said co-author of the study CheMyong Jay Ko, of the University of Illinois.

The clones of Snuppy might also provide insights into the development of cancer and other diseases, Ko said.

(Top photo from the National Post; bottom of photo by John Woestendiek)

To read more about the birth of dog cloning and how it became a big business, read John Woestendiek’s book, “Dog, Inc.

Chinese lab produces what it says is the world’s first “superdog” clone

longlong4

Chinese scientists say they have produced a “superdog” clone — and that the technology will enable them to mass produce dogs that are extra strong and extra fast.

And, unless you are a fan of the doggy version of eugenics, you might find that extra scary.

The beagle, named Long Long, was born in May, becoming one of China’s first canine clones and, the scientist’s maintain, the world’s first genetically modified canine clone.

“This is a breakthrough, marking China as only the second country in the world to independently master dog-somatic clone technology, after South Korea,” said Lai Liangxue, a researcher of Guangzhou Institute of Biological Medicine and Health with the Chinese Academy of Science.

The beagle puppy was genetically engineered by deleting a gene called myostatin, giving him double the muscle mass of a normal beagle.

longlongHe was one of 27 puppies created at Sino Gene, a biotech company based in Beijing — all clones of a laboratory research dog named Apple, according to published reports.

The researchers created 65 embryos through cloning, and genetically modified all of them.

Only Long Long had his myostatin deleted.

By combining genetic editing and cloning, scientists say they can produce “superbreeds” that are stronger and faster.

“With this technology, by selecting a certain gene of the dog, we can breed an animal with more muscles, better sense of smell and stronger running ability, which is good for hunting and police applications,” Lai said.

He also suggested that the gene-editing technology could be commercialized and further applied to create dogs with diseases such as autism, Parkinson’s and diabetes, for use in medical research.

It’s just the latest chapter in dog cloning, which has a frightening history and, potentially, an even scarier future.

Efforts to clone dog began in the U.S., with early research at Texas A&M funded by backers who saw cloning people’s pets — often sick, dying or even dead — as a profitable business enterprise.

Canine cloning wasn’t achieved until a few years later at Seoul National University in South Korea when Snuppy, the world’s first canine clone, was born in 2005.

The service would be offered to pet owners by several businesses, only one of which remains, Sooam Bioengineering Research Institute, the laboratory of controversial South Korean scientist Hwang Woo Suk.

longlong2Twelve years would pass before China became the second country to clone dogs — and clone them with a twist.

Lai says his team will be able to “batch produce” customized dogs through cloning and gene-editing, which in addition to possible military and law enforcement uses, would create an endless supply of dogs for use in laboratories by medical researchers.

The researcher has worked for years on genetically modifying dogs. By mastering cloning, and combining it with his gene-editing, he’s able to endlessly duplicate any successes he achieves.

As with Dolly the sheep and Snuppy the dog, Lai’s achievement is seen as ominous by some.

“It’s true that the more and more animals that are genetically engineered using these techniques brings us closer to the possibility of genetic engineering of humans,” David King, director of Human Genetics Alert, told the Express..

“That does set us on the road to eugenics,” King added. “I am very concerned with what I’m seeing.”

Me, too. Dog cloning raises some significant animal welfare concerns. Technology, especially when coupled with greed or ego, tends to run amok. Eugenics is a nightmarish pursuit, as is its canine version. Creating diseased dogs for medical research is just plain wrong.

On top of all that, this latest twist being touted by the Chinese researchers fails to recognize one simple fact:

Dogs are already super.

(Photos: Sino Gene)

A funny — and life-saving — thing happened on the way to the slaughterhouse

jindolThe four new arrivals at the Watauga Humane Society, a no-kill shelter nestled in the hills outside Boone, N.C., started adapting to their new lives not long after they were removed from a farm south of Seoul, Korea.

They continued to grow a little less timid and fearful of humans while they were quarantined in a sanctuary there, flown to the U.S., driven hundreds of miles to five different shelters and quarantined again.

Soon, they’ll be making the final step on the way to becoming pets, instead of meat.

twopartsThe four are among 31 dogs from Korea who arrived at no-kill shelters in North Carolina last week to be put up for adoption.

And those 31 are among 525 who have come to the U.S. and Canada since the beginning of last year, when Humane Society International added a new strategy to its campaign to bring an end to dog farms in Korea — closing them down one farm at a time.

Representatives of HSI, working with local animal activists in South Korea, have succeeded in shutting down five farms since then — usually by negotiating deals with the farmers and persuading them to pursue new, less brutal livelihoods.

One dog farm became a blueberry farm. Another switched from raising dogs to growing chili peppers. One dog farmer agreed to stop dog farming and, with help from HSI, started a water delivery business.

It’s only a small dent, given there are thousands of dog farms in South Korea, some with 1,000 dogs or more, all being raised to be sold for their meat.

farmdogskorea

They are commonly abused and neglected and spend their lives in crates before being sold to markets, where things get even crueler.

Farm dogs are sometimes boiled alive, sometimes beaten before slaughter under the belief that it makes their meat more flavorful. Their meat is sold to individuals and restaurants at open air markets, where you can pick a live one for butchering.

It’s all a perfectly legal tradition under laws in Korea, where a minority of the population still eats dogs, and many believe the meat offers health benefits, particularly in the summer months.

That minority is shrinking more as younger Koreans turn away from the practice, a fledgling animal welfare movement grows and the perception of dogs as family members becomes more widespread.

Perhaps, South Korea will, in time, outgrow the practice. Perhaps the Olympics coming to Seoul in 2018 — as it did in 1988 — will lead government officials, who did their best to hide it then, to take more meaningful steps.

Until then, animal activists — locally and globally — do what they can.

My first exposure to dog farms was seven years ago, when I went to South Korea to research a book I was writing on dog cloning. On the road to achieving that “feat,” researchers regularly bought and borrowed meat dogs from farms, using them for experiments, to help clone the first canine and to clone the dogs of pet-owning customers once the practice hit the marketplace.

I ended up at Moran Market — and quickly wished I hadn’t.

Images of what I saw then still pop up in my head, unasked. I’ll spare you the graphic details.

SONY DSC

It is estimated that more than 2 million dogs are slaughtered for human consumption in South Korea each year.

Add in those consumed in China, Vietnam and other Asian countries, and as many as 30 million dogs a year are killed for their meat.

South Korea is the only country where the practice has been industrialized. The New York Times reported in May that government data show there are more than 17,000 dog farms.

The Humane Society program is an attempt to shine a light on the issue, while also giving at least a few of the dogs a chance. On top of that, it strives to show that farm dogs, stigmatized in Korea and often perceived as different from pet dogs, are one and the same.

In one of the largest agreements brokered so far, this past May, a dog farmer in Wonju turned over all 260 of the dogs he was raising — mostly on discarded scraps he collected from restaurants — in exchange for certain considerations.

The particulars of the deal weren’t announced, but HSI offers incentives to farmers — $2,000 to $60,000 depending on the number of dogs involved — who agree to forfeit their dogs and get out of the business.

That farmer, Gong In-young, told the New York Times that many of the dogs were just weeks away from being sent to the slaughterhouse.

Gong, in addition to his farm dogs, had a pet dog, too. Asked about the difference in the lives of his farm dogs and his own dog, a spitz named Snow White, he described it as “the difference between heaven and hell.”

The most recent batch of dogs transported to the U.S. by HSI was small by comparison.

The dogs lived on a small farm in Jeonju, about 120 miles south of Seoul. A Canadian organization, Free Korean Dogs, was tipped off about it by local activists and, upon further investigation, learned it was an illegal operation.

While dog farms are legal, this farmer and his dogs were squatters, occupying land that didn’t belong to him. Law enforcement authorities were contacted and ordered the farmer and the dogs off the land.

That left the farmer willing to negotiate, and he eventually agreed to turn all 30-plus dogs over to a sanctuary at the end of July.

HSI, working with Free Korean Dogs, then took steps to have them shipped to the U.S., making arrangements for them to be taken in and adopted out by no-kill shelters who participate in the Humane Society’s Emergency Placement Partners program.

Those who participate in the program accept dogs the Humane Society has rescued — from everything from puppy mills to natural disasters.

All 31 farm dogs, after their flight and a few days in Maryland, were brought to shelters in North Carolina.

In the parking lot of a shopping center in Cary, the dogs were turned over to volunteers from local humane societies and shelters in the state, the News & Observer reported.

Those shelters included Cashiers Highlands Humane Society, Paws of Bryson City, Moore Humane Society in Carthage, Outer Banks SPCA in Manteo, and the Watauga Humane Society in Boone.

I visited the four who went to Boone last week.

I wanted to take some photos. I wanted to see how anti-social and fearful of humans they might be, or if that resilience dogs are famous for was already becoming apparent.

I wanted to understand how hard it might be for them to shake the past. Many who have adopted them say they’ve gone on to make greats pets — as has been the case with many of Michael Vick’s fighting dogs, puppy mill dogs and other dogs who have seen and suffered from the worst in humans.

And in the back of my head, which is also where those images of meat market dogs linger, I was thinking I might like to have one.

(For part two of this story, click here.)

(Photos: From top to bottom, Jindol, one of the four Korean dogs now at the Watauga Humane Society, by John Woestendiek; caged dogs at a South Korean dog farm, by Jean Chung for The New York Times; dogs awaiting butchering at Moran Market in Seoul, by John Woestendiek)

A modern day Dr. Frankenstein?

A controversial neurosurgeon in Italy said this week that he and his fellow researchers may be able to conduct the first human head transplant next year.

We suggest they start with their own.

Dr. Sergio Canavero has been compared to Dr. Frankenstein, and called a nut, but that hasn’t stopped him and members of his consortium — from China, South Korea and the U.S. — from severing the spinal cord of the beagle above (just so they could try to reattach it) and doing the same with numerous mice.

If that’s not weird enough, Canavero and team say that before they attempt a head transplant on a live human, they will conduct some experiments on human corpses, and then reanimate them with electricity to test his technique.

We can only assume they will do so in the basement laboratory of a castle, during a thunderstorm.

canaveroCanavero is director of the Turin Advanced Neuromodulation Group. He released three papers this week, and the video above, showing how he and his collaborators had successfully reattached the spinal cords of the dog and several mice.

Canavero also claims that researchers led by Xiaoping Ren at Harbin Medical University have already performed a head transplant on a monkey – connecting up the blood supply between the head and the new body.

Canavero’s short term goal is to successfully transplant a human head. His long term goal, he admits, “is immortality.”

What’s an acceptable number of dogs to torture in a quest of that nature?

We’d say none.

Canavero says the experiments on animals prove the technique used — known as GEMINI spinal cord fusion — incorporates a chemical called polyethylene glycol, or PEG, to encourage neurons to grow toward each other and connect.

He suspects it will also work in humans to fuse two ends of a spinal cord together, or to connect a transplanted head to a donor body.

He made the claims in a series of papers published in the journal Surgical Neurology International.

The claims have been met with widespread skepticism, according to New Scientist.

Canavero first announced his plans to conduct a human head transplant in 2013 and established the ead Anastomosis Venture, or HEAVEN, project to develop the techniques needed to carry out such an operation.

His collaborator in South Korea is Dr. C-Yoon Kim, a neurosurgeon at Konkuk University in Seoul who partially severed and reattached the spinal cords of 16 mice. Five of the eight mice who received PEG regained some ability to move. The other three died — as did eight who were in a control group.

In another experiment the South Korean team nearly severed the spinal cord of a dog. While the dog was initially paralyzed, three days later the team reported it was able to move its limbs and wag its tail.

South Korea is also the birthplace of dog cloning and up until this summer — when an American company cloned a dog for a customer — it was the only country cloning dogs for profit.

It’s probably not too outlandish — given all the bizarre turns medical researchers are taking — to wonder if surplus canine clones in South Korea end up being used for other wacky experiments by mad (or at least overly zealous) scientists.

In fact, if you look at its history, creating dogs for medical research use was one markets mentioned by the developers and marketers of dog cloning.

Could it be that some of the ideas initially presented in science fiction might ought to remain in the realm of science fiction?

Canavero’s research papers don’t indicate how many more dogs might have their necks snapped or heads severed by his research team as they boldly and single-mindedly stride toward their goal.

But, again, we’d argue that — no matter what medical gains it could lead to for humans — it should be NONE.

Dog clones: Now made in America

nubia2

Just as the earliest efforts to clone a dog in America didn’t make a huge splash, news-wise, neither did the recent birth — nearly 20 years later — of the first made-in-America canine clone.

ViaGen, a genetic preservation company in Texas, announced at the end of July that the first successful cloning of a dog in America had led to a birth, and that the Jack Russell terrier pup had been delivered to clients.

Chances are you haven’t read about it — because hardly anyone has written about it.

Including me — the guy who wrote that dog cloning book.

I received an email Monday containing the press release announcing the successful cloning. It came from Andrew Lavin, a public relations consultant in New York who handles publicity for ViaGen. It was dated Sept. 12 and included the photos of the clone, named Nubia, that you see here.

When I checked online to see what news coverage the announcement had received, I found almost none — only an “article” in Pet Age magazine (actually a verbatim reprint of the company press release) in July.

When I called ViaGen’s Austin offices to clear up some of my confusion I was told the press release had originally been issued at the end of July, and they didn’t know why the one I received had been re-dated to Sept. 12.

When I asked why the announcement had not received greater news coverage, the person on the phone said only, “It was a soft press release.” She didn’t explain what that meant.

(I can only guess it means a press release sent to a limited few, vague and fuzzy on the details, and accompanied by a “we’re not going to answer any questions” attitude — one that is low-profile enough to not arouse any detractors, such as the many animal welfare organizations that frown on cloning pets, saying it is cruel to animals and exploits bereaved pet owners.)

When I asked ViaGen for more information about the cloning, I was told, “all media requests go through Andy,” meaning Andrew Lavin.

He eventually returned my call and answered my email, explaining that he had “updated” the original press release — and therefore changed the date on it.

He did seek answers to my questions and sent me ViaGen CEO Blake Russell’s responses to them. Russell sidestepped far more than he answered.

nubia1The owners of the clone are not being identified — apparently not even the state or country where they reside.

Their original dog is deceased, but they were able to have her cloned with tissue samples taken by her vet when she was spayed.

Asked where the other dogs that are needed to produce a successful clone came from — dogs in heat from whom egg cells are harvested, and female dogs who serve as surrogates — Russell said ViaGen Pets purchases oocytes from an unnamed provider and that “ViaGen Pets uses a production partner to supply the needed surrogates.”

Presumably, the merging of egg and donor cells and the surgeries necessary were performed at ViaGen labs in Texas.

Texas, by the way, is where the whole crazy idea got started — though it wasn’t pulled off until scientists in South Korea cloned the world’s first dog.

Here’s the condensed version:

Shortly after the birth of the world’s first cloned mammal, Dolly the sheep, in 1996, the wealthy founder of the University of Phoenix, John Sperling, decided that cloning his girlfriend’s dog, Missy, would make for a lovely gift.

He teamed up with his girlfriend’s son, Lou Hawthorne, to find a learning institution that would be interested in cloning the world’s first dog.

They chose Texas A&M University and funneled millions into the project.

For years, from 1998 to 2002, researchers there tried to clone a dog. They were able to clone the world’s first pig, cat, bull and goat, but dogs, they found, were extra difficult.

Hawthorne had high hopes of turning the cloning of pet dogs into a big business, and it was during this time that he launched Genetic Savings & Clone, a company that, like Viagen, stored the cells of pets whose owners thought they might someday want a clone.

Snuppy

Snuppy

The research project at Texas A&M, eventually, was dropped, but the quest was picked up by Seoul National University in South Korea, which produced the first dog clone, Snuppy, in 2005.

The thousands produced since then — most often for bereaved pet owners seeking a duplicate of the dog they lost — have all been made in South Korean laboratories.

At one point, two Korean companies were producing dog clones for customers, and one American company was selling dog cloning, too.

Bio Arts, a company Hawthorne started in hopes of cloning dogs on its own, ended up teaming up with one of the Korean companies, Sooam, led by former Seoul National University scientist Hwang Woo Suk, to provide clones to American customers.

Among the first of those shipped back to the U.S. was a clone of Missy, which he presented to his mother, Sperling’s girlfriend.

She noted the puppy was ill-behaved, and said she didn’t want it.

SONY DSC

Surgery at Sooam

Hawthorne later pulled out of the partnership with Sooam, citing, among other reasons, his concerns that accepted animal welfare protocols — or at least those accepted by most Western countries — weren’t being followed by the South Koreans.

“A cloned dog contributes to the happiness of a family but I do not think it is possible to do it without a huge amount of suffering to hundreds of others,” Hawthorne told The Mirror, which was reporting on the first dog cloning for a customer in the UK.

In an interview with the Mirror, Hawthorne referred to the vast numbers of dogs that it took — up to 80, he said — to clone just one. And he confirmed that, as my book reported, Korean cloning researchers borrowed dogs from dog farms — farms where dogs are raised for their meat — for the process.

Today, only one of the Korean companies is still in operation.

https://www.amazon.com/Dog-Inc-Uncanny-Inside-Cloning/dp/1583333916Another Korean company that paved the way for cloning pet dogs — and provided the first clones to an American customer — pulled out of cloning pet dogs in 2011, not long after the publication of my book, “DOG, INC: The Uncanny Inside Story of Cloning Man’s Best Friend.”

ViaGen’s successful cloning of a dog lessens the likelihood of dog cloning fading away; instead it brings the process to American shores, and offers it at a much reduced price — $50,000 instead of the initial $150,000 the Korean companies charged.

ViaGen Pets says it is now the only American company offering pet cloning services — and says they are doing so “in full compliance with all U.S. regulatory standards and humane pet care practices.”

The are no federal laws against cloning dogs, or for that matter, humans, in the United States.

ViaGen,a long-time cloner of livestock, produced its first cloned cats for customers last year and it has been banking the cells of pets for more than a decade.

The company says the birth of Nubia will likely increase demand for cloning and genetic preservation of companion pet DNA.

screencapture-viagenpets-1473861354711

President Blake Russell said the company has already genetically preserved almost 1,000 pets and that there is a waiting list for the cloning procedure.

“The potential to have an identical twin to something that was very important and special in your life is an unprecedented opportunity and has brought a lot of joy to pet owners,” Russell says in the press release.

In addition to the cost of cloning, ViaGen charges a $1,600 fee and $150 a year to store tissue samples from pets whose owners may someday want to clone them.

The cloning procedure involves injecting cells harvested from the original dog into egg cells harvested from female dogs, a jolt of electricity to help them merge, and implanting the resulting embryo into a surrogate mother dog who carries the pup to birth.

ViaGen says a cloned puppy or kitten is “simply a genetic twin born at a later date, and should share many of the original’s attributes, including intelligence, temperament and appearance.”

The South Korean company guarantees only that the appearance will be identical, or nearly identical — but they often achieve that by producing multiple clones.

Many of dog cloning’s customers have come from the U.S. and the U.K. — and up to now they have been turning to Sooam Biotech to clone their dogs.

Most animal welfare organizations oppose the practice, pointing to the number of other dogs it takes to produce a clone, the intrusive procedures, the creation of surplus clones, and the sometimes nightmarish results. They also say pet cloning companies are exploiting the grief of bereaved pet owners.

There has been little outcry from them about the fact that dog cloning is now being done in America. Then again, it’s a development of which many people — possibly having missed that “soft” press release — aren’t aware.

In any case, it appears an American-born idea has finally — for better or worse — come to fruition in America.

(Photos of Nubia courtesy of ViaGen Pets; photos of Snuppy and a cloning underway at Sooam by John Woestendiek)