This ad for Trifexis depicts a dog living in a bubble — albeit it one that’s outside and has plenty of tubes to run around in.
It serves to protect him from heartworms, hookworms, roundworms, whipworms, flea infestations and all those other frightening hazards that exist in that place where dogs, for centuries, managed to survive:
What we find most interesting about it, though, are the disclaimers, which seem to have risen with doggie prescription drugs to the same level they have with human ones, where three-fourths of the advertisement are devoted to a listing of potential scary side effects, quickly recited in monotone, in hopes you — or your dog — won’t really hear them.
With Trifexis, it goes like this: “Treatment with fewer than three monthly doses after the last exposure to mosoquitoes may not provide complete heartworm prevention. The most common adverse reactions were vomiting, itching and lethargy. Serious adverse reactions have been reported following concomitant extra-label use of ivermectin with spinosad alone, one of the components of Trifexis.”
On top of the warnings recited, more appear in small print during the ad:
“To ensure parasite protection, observe your dog for one hour after administration.”
“If vomiting occurs within an hour of administration, give another full dose.”
“Puppies less than 14 weeks of age may experience a higher rate of vomiting.”
In their print ads, the makers of Trifexis additionally advise the drug be used with caution in breeding females, and in dogs with epilepsy. Its use in breeding males has not been evaluated. Print ads also list lethargy, depression, decreased appetite and diarrhea as possible side effects.
The chewable, beef-flavored tablets — administered once a month – are a combination of spinosad and milbemycin oxime, and they serve to prevent heartworm disease, kill fleas and prevent infestations and treat hookworm, roundworm and whipworm infections.
The tagline for the ad is “You don’t have to go to extremes to protect your dog from parasites.”
Apparently you do, though, if you’re selling prescription drugs — for canines or humans — to protect your ass from lawsuits.
To see all our “Woof in Advertising” posts, click here.
Posted by jwoestendiek May 21st, 2013 under Muttsblog, videos.
Tags: animals, appetite, bubble, canine, caution, chewable, depression, diarrhea, disclaimers, disease, dog, dogs, drugs, environment, fleas, health, heartworm, hookworm, human, infections, itching, lethargy, loss, mosquitoes, parasites, pets, prescription, prevention, protection, roundworm, safety, side effects, tablets, trifexis, tube, veterinarians, veterinary, vomiting, warning, whipworm
A Texas judge ruled yesterday that a dog who was missing her nose when she was found wandering in a field should not be returned to her original owners.
“I find that this dog was unreasonably deprived of care,” Hutto Municipal Judge Lucas Wilson said of the dog, named Victory by her rescuers.
Animal control officers initially believed she’d been the victim of abuse, but Victory’s owners, when they came forward to reclaim the dog, said she suffered from an autoimmune disease that ate her nose away.
The court ruling, which came after a four-hour hearing, means the bearded collie will remain in the care of Austin Pets Alive, which will place her in a new home.
Josh Fogelman, an attorney for the owners, Shawn and Candice Lance, said after the ruling that the owners took good care of the dog, who they called Olive, and never abused her.
“I believe this is a witch hunt,” he said after the ruling. According to the Austin American-Statesman, Fogelman was unsure whether the Lances would appeal the ruling.
Hutto police found the dog wandering in early January and took her to a local veterinarian. She was later placed in foster care by Austin Pets Alive, a local animal welfare organization that raised $15,000 in donations for her. Victory was scheduled to receive a skin graft, but that was canceled when her owners called police in February to reclaim the dog.
Shawn Lance, who recently moved from Amarillo, said he had taken the dog to a veterinarian there three times after her nose started to scar and lose color. The medicine the vet prescribed made the dog sick, though, so he took her off it, he testified.
Lance, a financial adviser for Edward Jones who said he worked for several years as a veterinary technician, testified that he and his wife tried to find the dog after she disappeared by putting up a missing poster at a community mailbox and calling an animal shelter.
He said that the dog lost her nose when he took her to a veterinarian.
No charges were filed against the Lances, but a judge was asked to intervene to determine whether Victory should be returned to them.
Judge Wilson said that Shawn Lance made an unreasonable decision to “wean her off of medication” and said veterinary records don’t indicate the dog, at the time of her last visit, had lost her nose.
“If you look at the veterinary records they say the nose is raw but still there,” he said.
While it’s possible the dog lost her nose to disease, the judge said, evidence indicated the pet was being deprived of proper care.
Posted by jwoestendiek March 7th, 2013 under Muttsblog.
Tags: abuse, animal control, animals, austin pets alive, autoimmune, bearded collie, care, denied, disease, dog, dogs, hutto, judge, lost, lucas wilson, neglect, no nose, nose, noseless, pets, proper, ruling, suspected, victory
After a Valentine’s Day hearing, a Texas judge will decide who should have custody of Victory, a bearded collie who is missing her nose.
Victory was found last month wandering in Hutto, Texas, outside of Austin. Her fur was heavily matted. She’d sustained puncture wounds. And her nose appeared to have been cut off.
Since then, an owner has stepped forward, saying Victory (not her original name) had run off a month earlier, and that the loss of her nose was the result of an autoimmune illness she was being treated for.
After she was found, the 4-year-old dog was treated by a local veterinarian, then placed in a foster home by Austin Pets Alive, which began a fundraising campaign and raised $2,000 for the dog to undergo skin graft surgery on her nose last week.
The surgery was canceled after a man called saying he owned her and wanted her back, said Laura Stromberg Hoke, a spokeswoman for Austin Pets Alive.
A judge will hear the matter Thursday, deciding whether the dog should be returned to her owner or remain with Austin Pets Alive, according to the Austin American-Statesman. No charges have been filed in the case, but police say they “wanted a judge to hear the information they had gathered during the investigation.”
Hutto animal control officers found the dog Jan. 9, and initially suspected she’d been the victim of abuse. The owners of the dog — who authorities refused to name — said she had run away around New Year’s, according to Hutto Police Chief Peter Scheets.
Police say they are still investigating whether the dog lost her nose due to medical neglect or abuse. Veterinary records show that the dog was last treated for lupus nine months ago but had no follow-up treatment, the police chief said.
One type of lupus that occurs in dogs can cause redness, scabs and ulcerations on a dog’s nose.
Scheets said there is also a possibility that the dog was injured after she escaped from her home and before she was discovered by police.
The hearing is open to the public and will be at 4 p.m. Thursday (Feb 14) in Hutto Municipal Court, 401 W. Front St.
You can find an update on this story here.
(Photo: Austin Pets Alive)
Posted by jwoestendiek February 13th, 2013 under Muttsblog.
Tags: abuse, animal cruelty, animals, austin, austin pets alive, bearded collie, courts, custody, cut off, disease, dog with no nose, dogs, foster, found, hutto, investigation, lupus, missing, no nose, nose, noseless, owner, pets, texas, victory
A lot of us are so dependent on our dogs we’d list them right up there with oxygen.
For Alida Knobloch, her dog is oxygen.
The three-year-old Georgia girl, who has a rare lung disease called neuroendocrine cell hyperplasia of infancy, or NEHI, breathes through a tube most of the time, attached to an oxygen tank, which is attached to her dog.
Her goldendoodle, Mr. Gibbs has been specially trained to tote the 6-pound tank, and to stay at Alida’s side.
Alida started having breathing problems by the time she was 6 months old, according to an MSNBC report. One day she turned blue and her parents, Aaron and Debbie Knobloch, rushed her to the hospital. Doctors stabilized her, but were baffled as to what her problem was.
Eventually, a specialist diagnosed NEHI, a condition that was only discovered in 2005, There have been only 500 confirmed cases.
With the help of a small portable oxygen tank, Alida’s health improved, but cumbersome and limiting as that was for a toddler, her parents started looking for ways to make her life more normal.
According to the Daily Mail, the couple learned about service dogs from a TV program and started searching for a guide dog who could learn the necessary skills. When they heard about a trainer in Georgia, with a dog that was available, they moved from Utah to Georgia to work with her.
Mr. Gibbs was living with trainer Ashleigh Kinsleigh, and had finished his initial obedience training when the Knoblochs first visited.
“He had to learn to get under the table at restaurants,” Kinsleigh said. “He had to learn that if there were other animals he couldn’t just go and play with them. He had to stay right next to his girl and ignore all the fun things around him. He also had to build up to be able to carry around the full weight of the 6-pound tank.”
“His job is to go wherever she goes and do whatever she does,” Kinsleigh added. “If she wants to get on the bike and go down the driveway he has to learn to run alongside. If she’s going to ride on a slide, he has to learn to climb up and slide down behind her.”
Experts say that children with NEHI often outgrow the disease, or the condition becomes so mild they no longer require additional oxygen.
(Photo: Caters News Agency / Daily Mail)
Posted by jwoestendiek March 22nd, 2012 under Muttsblog.
Tags: alida knobloch, animals, Ashleigh Kinsleigh, assistance, breathing, condition, dependence, disease, dog, dogs, georgia, gibbs, girl, goldendoodle, guide, help, lung, mr gibbs, nehi, neuroendocrine cell hyperplasia of infancy, oxygen, oxygen tank, pets, portable, rare, service, trainer
Was he part German shepherd, as most people guessed? Maybe some mastiff, or Great Dane, to account for his size? Some thought they detected retriever, or ridgeback, Catahoula or coonhound. It was a true whodunit – who exactly got together to produce such a beast? What made him so big? Where’d that curly tail come from?
It was an enjoyable mystery, unlike the kind of guessing game that becomes more common as a dog ages.
Then it becomes not what he’s got in him, but what he’s got. (I know that’s bad grammar, but I like it better, and I’m in control, at least of the words on this page.)
It’s amazing, and depressing, all the things that can go wrong with dogs, not to mention us. And the path to figuring out which one has – even when you do have medical insurance — can be torturous.
Breed determination tests require just a simple swabbing of the inside of the cheek (or a blood test), but determining what’s wrong with your dog will likely take numerous even more expensive ones that may or may not yield an answer, or even a general category into which his ailment falls.
Is it orthopedic, neurologic, digestive, cognitive? Or could it be, instead of a purebred disease or disorder, some sort of mix?
But first things first, or at least now. Ace seems back to normal. Unlike the previous two days, when he was a mix of clingy and anxious and, while he would sit, refused to lay down – an American Clinganxious Setter, maybe? – he’s himself again, and seems to have no complaints.
He’s back on the futon as I write this — one of the areas he has avoided for the past two days – back in the role of muse, as opposed to object of my fretting. He’s laying — or is it lying — down at will. He’s eating, drinking, pooping, peeing, playing and breathing normally.
A visit to the vet — and yes, I still want to marry a veterinarian — brought no definite answers. A battery of blood tests showed that liver, kidneys and pancreas were all clear, and that he had an only slightly elevated white blood cell count.
He was dispensed some anti-inflammatory pills, which may or may not account for his improvement. Still, upon the vet’s recommendation, I will engage in the also-not-fun, though highly challenging, game of catching one’s dog’s pee in a cup, and will tote a urine sample to their office this week.
Then, depending on what the pee reveals, and depending on whether he shows any more symptoms or strangeness, more tests are a possibility — X-rays of his stomach to ensure no parasites or other foreign objects are lurking there, neurological tests because of his earlier problems, and a day-long test for Cushing’s Disease, which the vet mentioned was also a possibility.
Or, given what appears at least today as an apparent recovery, was it nothing at all? For all I know it could have been the full moon, a ghost, a sound he was hearing that I wasn’t, or an extended blonde moment, even though he’s more auburn.
Adding to the uncertainty, when your dog appears to be ailing, there’s always the question you ask of yourself, or at least I ask of myself: Am I under-reacting, or over-reacting? The answer of course is that, in circumstances like these, over-reacting is preferable, if not good for the bank account.
For you newcomers who haven’t memorized Ace’s breeds, I won’t repeat them here. You’ll have to look it up, just in case I ever move to one of those backward towns that enforces or is instituting breed bans — though I probably wouldn’t — but in the event of which Ace is a collie.
Let’s just say, of those breeds that showed up in the three DNA tests he has had in the past two years, one is Japanese, one is Chinese, one is German (but not a shepherd) and one is an overused and misunderstood catch-all that’s not really a breed at all.
As for all those friends and readers who have offered their opinions, I do appreciate the input, the sharing of your own experiences, and the support.
As for Ace, once he wakes up, I think he’s due for a not-too-strenuous hike.
It’s always good to work a little sunshine into the mix.
Posted by jwoestendiek December 18th, 2011 under Muttsblog.
Tags: ace, ailment, animals, behavior, breed, cushings disease, diagnosis, disease, disorders, dna, dogs, guess, guessing, health, identification, medicine, mix, mutt, mystery, pets, strange, tests, travels with ace, uncertainty, veterinarian, veterinary, won't lay down
On the first morning of our camping trip, your intrepid trio — foursome counting Ace — decided to take an impromptu hike, just a slow and casual one, following the Davidson River upstream for a ways to see where it took us.
Our first stop was at a fishing/swimming hole, where a few campers were trying their luck, including a woman who had just learned to fly fish. She hadn’t had much luck that morning, but before that she’d caught some, and she whipped out her cellphone to prove it, clicking her way to the correct photo, then holding it up for us to see, as one might hold up a just-caught fish.
In it, she said, there appeared the ghostly image of a little girl that wasn’t there when the photo was taken.
Not having my glasses, I really couldn’t distinguish anything. But as my two friends seemed amazed, I pretended I was, too, nodding my head and saying ”wow.”
We walked on a bit, Ace being more than up to the task. This is his favorite part of camping — blazing a new, to him, trail.
At one point he clambered up a three-foot tall tree stump. At another he darted in and out of the water, then jumped atop a four foot wall. He showed absolutely no sign of his back bothering him. Despite his fear of the campfire, and the noises it produced, the night before, he was, after two long months, starting to act like himself again. Perhaps the camping trip — as camping trips can do — was curing what the drugs couldn’t.
He ran. He played. The stiffness that seemed to have been bothering him was gone. And when he shook, it was all out, with gusto — not that fearful tentative headshake he has been doing of late.
When we came to a fork in the trail, we let Ace pick the direction, and he chose left — up a mountain, instead of following alongside the river. Not a rigorous climb, by any stretch, but I still felt it necessary to inform my two doctor friends that I had imaginary peripheral artery disease (IPAD).
Understand that once a disorder/disease/infirmity gets advertised on TV, I become convinced I have it — not enough to talk to my doctor about whatever drug the ad is for, not enough to submit to the numerous side effects the drug ads list, but enough to fret. That’s why I also have imaginary mesothelioma, though, according to advertisements, you want to talk to your lawyer about that, as opposed to your doctor. The cure for that, apparently, is a lawsuit.
(Disclaimer: These diseases are no laughing matter, even though the advertisements, in which drug companies and law firms feign great concern for your well-being, are.)
“Yes,” I explained to Dr. John, “that peripheral artery thing, I’m pretty sure I have it. My legs get tired when I walk uphill.”
This low grade climb didn’t seem to bother me, though. Perhaps Ace’s return to normal was putting a little more spring in my step. I’m convinced our dogs reflect us, and us them — both when it comes to personality and how we’re behaving at a moment in time. What’s harder to figure out, often, is who is doing the projecting and who is doing the reflecting. Am I, for instance, behaving lethargically/bufoonishly/fearfully because Ace is, or vice versa?
Am I low key because he’s low key, or is he low key because I’m low key, and are we both feeding off each other’s low keyedness and becoming more low keyed yet, and, if so, how low can we go before we’re both asleep?
We were both wide awake on this walk — me due to five or so cups of hearty campground coffee, Ace, I think, because of the newness and the nature. When we came to a weathered wooden sign that said “old cemetery,” we followed where it pointed.
After a couple of switchbacks we came to a hill from which a dozen or so gravestones protruded from the ferns. If the stones had names on them, few of them were legible anymore — except for the one pictured at the top of this post.
Buried beneath it was Avo Sentell, who had just turned five when she died — the same day in 1916 as her mother, Susan, who is buried next to her.
We paused, and grew more sober. Amid towering trees – some thriving, some rotting, some dead — we speculated on what it could have been that killed both mother and daughter on the same day.
I told myself I should stop joking about deadly diseases — even though that is how I cope with my own immortality. Call it a survival skill.
Back home after my camping trip with college buddies, I Googled Avo Sentell — Googling being a generally safe activity, whose only side effects are eye strain, carpal tunnel syndrome and terminal frustration over all the garbage, pop-up and otherwise, that litters the Internet.
Through one of those grave-finding websites, I learned that Avo and her mother were killed in a landslide in Pisgah National Forest during the Great Flood of 1916.
Both were buried at the site of their deaths. I found a group photo that contained Avo — she’s the third from the left in the second row in this picture of the entire student body of English Chapel School. Seeing how tiny she was wrenched my heart a little more.
That mystery resolved, another remained.
It was not whether Avo was the image in the fisherwoman’s photo. We’re not, much, prone to believing in the supernatural, and I doubt Avo’s ghost is haunting the mossy, fern-studded hills — even though we were in Transylvania County.
What I was left wondering about was the tiny pink mitten that was draped over her tombstone. On the mitten are the words “Always Trouble.”
I doubt it was left there as a commentary on her – for the mitten was too modern, and who is left to remember a girl who died 95 years ago? Besides, Avo appears to have been too small to have caused a significant amount of trouble in her life, much less “always.”
Maybe it was dropped by a hiker. Maybe someone else picked it and placed it there so someone might find it. Maybe it was left there as a gift, or commentary on life, by a stranger, or a descendant of the Sentell family.
A bouquet of yellow plastic flowers was at the base of the stone, which was clearly an upgrade — it’s too clean and clear and modern to have been the one that was originally there.
To me, it was also a reminder. Life is fleeting, and sometimes unfair, and there is always — somewhere — trouble. We work. We laugh. We play. We cope. We die.
Sometimes, before the journey’s over, we tackle those troubles. Sometimes we ignore them. Sometimes we joke about them. Sometimes we’re too rushed to pay them any mind at all. Sometimes we let them weigh us down to an unhealthy degree.
At times like those, friends come in handy.
At times like those, a walk in the woods — with your dog — is good.
Posted by jwoestendiek May 27th, 2011 under Muttsblog.
Tags: 1916, ace, america, avo sentell, campground, camping, coping, cures, davidson river, death, disease, doctors, dog's country, dogscountry, drugs, fears, flood, ghosts, grave, hike, hiking, illness, imagination, lawyers, life, mountains, nature, north carolina, pisgah national forest, road trip, symptoms, travels with ace, woods
If the following take on Westminster reads like its coming from some PETA hothead that’s because it is.
Then agains, hotheads are sometimes worth listening to.
Lindsay Pollard-Post is a staff writer for The PETA Foundation, and her remarks appeared in the form of a guest column in the Sacramento Bee.
Pollard-Post recounts watching Westminster in her youth, usually with a bad case of strep throat, and with her dog Katie at her side…
“But had I known then that Westminster – and the dog-breeding industry that it props up – share the blame for the mutilation and deaths of millions of dogs each year, I would have changed the channel faster than you can say ‘Sesame Street.’
“Back then, I had no idea that the snub-nosed bulldogs and pugs prancing around the ring may have been gasping for breath the whole time because these breeds’ unnaturally shortened airways make exercise and sometimes even normal breathing difficult. I didn’t know that the “wiener dogs” that made me laugh as their little legs tried to keep up may have eventually suffered from disc disease or other back problems because dachshunds are bred for extremely long spinal columns. I didn’t learn until much later that because of inbreeding and breeding for distorted physical features, approximately one in four purebred dogs suffers from serious congenital disorders such as crippling hip dysplasia, blindness, deafness, heart defects, skin problems and epilepsy.
“I remember feeling shocked when I learned that Doberman pinschers’ ears naturally flop over, and that their ears only stand up because they are cut and bound with tape when the dogs are puppies. And I felt sick to my stomach when I discovered that cocker spaniels have beautiful, long, flowing tails, but American Kennel Club breed standards call for their tails to be amputated down to nubs. The American Veterinary Medical Association says that these procedures ‘are not medically indicated nor of benefit to the patient’ and they ’cause pain and distress.’
“… Like many people, I hadn’t made the connection that every time someone buys a purebred dog from a breeder or a pet store, a dog in a shelter – a loving animal whose life depends on being adopted – loses his or her chance at a home …
“Dog shows also encourage viewers to go out and buy purebred dogs like the ones they see on TV from breeders or pet stores. This impulse buying robs shelter dogs of homes, and even more dogs end up homeless when overwhelmed people discover that the adorable puppy they bought ruins carpets, needs expensive vaccinations and food and requires their constant attention.
“My own parents succumbed to the lure of purebreds: They purchased Katie from a breeder. Katie was an exceptional dog and my best friend, but it saddens me to think that other loving dogs waiting behind bars in shelters missed out on a good home because we thought we needed a certain breed of puppy.
“Thankfully, some things have changed. After Katie passed away, my parents adopted a lovable mutt from the local shelter. I haven’t had strep throat since I was a teenager. And if the dreaded illness strikes again, you’ll find me cuddling on the couch with my rescued dog, Pete, watching movies – not Westminster.”
Posted by jwoestendiek February 16th, 2011 under Muttsblog.
Tags: adopt, american kennel club, animals, appearance, back, breeding, bulldogs, congenital, criticism, dachshunds, disease, disorders, distorted, docking, dog shows, dogs, ears, features, hip, homeless, impulse buys, inbreeding, kennel club, leg, mutts, pets, physical, problems, purebreds, shelters, tails, westminster
He further advises that anyone who is licked by a dog wash the area immediately.
To me, a guy who has spent the last eight months with my dog nearly constantly at my side during our travels across America — including in whatever bed we happen to be sleeping in at night — that seems a massive over-reaction.
Bruno Chomel, a professor at the School of Veterinary Medicine at the University of California, Davis, says that, while such cases aren’t common, people have contracted infections from sleeping with, kissing and being licked by their pets. Chomel and fellow researcher Ben Sun, of the California Department of Public Health, express their views in the latest issue of the journal Emerging Infectious Diseases.
I don’t subscribe to that publication, because my theory is the surest way to get a disease is not from sleeping with your dog, but from reading about that disease.
Though I sleep with my dog nightly, I’m not so much concerned about Zoonoses, or diseases transmitted to humans by animals, as I am about Merckitis, a chronic case of which I’ve suffered from since childhood.
It stemmed from a big blue book called The Merck Manual, on my mother’s bookshelf, which allowed you to, based on your symptoms, diagnose your medical issue, read about the treatment and determine, in my case, if I was going to live to see 13.
I must have diagnosed myself with a dozen different diseases, many of them fatal, in the course of matching up my symptoms — usually those of a common cold — with the worst possible maladies.
I remember one night that — congested, unable to breathe through my nose and worried that my throat breathing pipe (non-medical term) might close up – I gathered the necessary supplies to perform an emergency tracheotomy (bic pen, with the ink part removed, pocket knife, duck tape) and kept them under my bed, alongside the book.
The Internet has made it much easier to wrongly self diagnose — just a few clicks and you can jump to the conclusion that you have the most dreaded disease imaginable. The key word there being imaginable. In a way, those medical self-help websites, rather than lessen the need for doctors, only create more of one as we, fueled by our fears, rush to confirm our faulty self diagnoses.
Pulled muscle? I was sure it was a heart attack.
Of course, such concerns are not always entirely baseless, and many of them should be checked out by professionals. But often, they’re only in our heads — having been placed there by WebMD, yourdiagnosis.com, familydoctor.org and the like. Often they are really far-fetched, instilling a fear out of all proportion with reality, which is the case with Chomel’s study, or at least his remarks:
“I think pets can be very nice in the home environment, but certainly, they don’t belong on the bed,” Chomel told LiveScience.
Chomel says humans can contract bubonic plague from flea-infested pets, bacterial infections resistant to multiple strains of antibiotics, and various parasitic worms.
Since 1974, Chomel says, multiple cases of plague have been associated with people in the southwestern U.S. who allowed flea-infested cats to sleep with them. And in a 2008 outbreak, a study found that people infected with bubonic plague were “more likely to have shared a bed with a dog than uninfected counterparts.” (Despite that, I still don’t recommend sharing a bed with uninfected counterparts.)
The authors cite surveys conducted in the U.S., the United Kingdom, France and the Netherlands that show up to 45 percent of dogs sleep in their owners’ bed.
Several reports of bacterial infections have been attributed to sharing a bed with pets, and in “multiple” cases, they report, patients acquired various infections after allowing their dogs or cats to lick wounds or damaged skin.
That’s the total opposite of my philosophy. Whenever I get a boo-boo, the first thing I do is let Ace lick it. Then it feels better. If thousands of microscopic parasites enter my bloodstream by doing so, so be it … join the party, fellas.
Don’t tell me not to sleep with my dog, especially when it’s this cold. That’s like saying, because there may be some impurities in the air, I should stop breathing. I’m going to continue to engage in both risky behaviors.
And if worse comes to worst I can always, after consulting my Merck Manual, perform an emergency tracheotomy.
OUR FAVORITE READER COMMENT: “Pity poor Chomel. He has obviously not enjoyed the delight of a canine companion…I’ve spent the past 50 years sleeping with dogs – most of the canine persuasion – and if anything it must have strengthened my immune system … The plague? Only a plague of comfort and love. Poor Chomel.”
(For all the comments on this post, click the comment button below, and scroll to the bottom to leave one of your own.)
Posted by jwoestendiek January 24th, 2011 under Muttsblog.
Tags: animals, bruno chomel, bubonic, davis, diagnosis, disease, dog, dogs, emergency, fleas, germs, infection, infectious, kisses, licks, medical, parasites, pets, plague, research, science, self diagnosis, self help, sick, sleeping with dogs, tracheotomy, transmit, transmitted, university of california, veterinary, zoonoses, zoonosis
Given the endlessly rising popularity of dogs, and our increasing emotional attachment to them, medical researchers who use them for experiments can expect stronger and growing opposition to the practice from the public, a leading expert in canine-human interaction told a conference at Johns Hopkins University this week.
James Serpell, director of the Center for the Interaction of Animals and Society at the University of Pennsylvania School of Veterinary Medicine, was the keynote speaker at a conference sponsored by the Center for Alternatives to Animal Testing at the Bloomberg School of Public Health.
The 30-year-old, non–profit center promotes humane science by supporting the creation, development and use of alternatives to animals in research, product safety testing, and education. It seeks ways to replace animals with non-animal methods, reduce the numbers of animals necessary, or refine methods to make them less painful or stressful to the animals involved
Serpell and other speakers both pointed out that after decades of declining, the use of dogs in medical research has increased in the last couple of years.
U.S. Department of Agriculture figures show that the number of dogs used in medical research and testing dropped from 200,000 in 1973 to 66,000 in 2007, said Tanya Burkholder, chief of the Small Animal Section at the National Institutes of Health. Now, she said, the number has risen to about 75,000 a year.
Much of the increase is likely a result of advancements in, and the promise of, gene therapy.
Dogs have always been a valuable research model for scientists, going as far back as Aristotle’s day. Their size, physiology and cooperative behavior have made them convenient models for scientists, who, like Pavlov’s dog, grew conditioned to using them in experiments.
While public opposition to subjecting dogs to medical experiments resulted in the practice dwindling in recent decades, the use of dogs has crept up again in the last two years due to advances in molecular biology, genetics and the sequencing of the canine genome.
Because dogs get about 220 of the same inherited diseases and disorders that humans do — including Alzheimer’s, muscular dystrophy, hemophilia and retinal degeneration – medical researchers are able to study the underlying genetic defects and, through dogs, seek cures.
This means dogs are being bred to be born with the diseases in colonies at U.S. universities and research institutes and, in the case of South Korea, cloned to be born with the diseases.
No one at the conference went so far as to suggest a halt to using dogs in research, but Serpell warned that the practice does come with risks, and a price.
Dogs evoke protective and nurturing instincts in people, and those have grown stronger as the dog-human relationship has evolved — to the point that dogs are viewed more as family members than family pets. Public opposition to the laboratory use of dogs has continually grown in the last few decades.
Researchers need to be cognizant not just of society’s strong feelings about dogs, but also about dog’s strong feelings for humans, Serpell said. “Many dogs undergo severe distress when contact with a human is limited or thwarted. We don’t give that regard sufficient credence,” he said.
The stronger attachment to dogs is in part due to breeders focusing on creating animals for purposes of human companionship, unlike in the past when they were bred for the work they could do. Serpell noted that baby-like features, for one thing, appeal to humans.
Showing photos of dogs, Serpell pointed to one and said, “This animal looks like it was invented by Walt Disney.”
Our attraction to dogs stems too from the fact that they make eye contact with humans more than any other species, and studies have shown that petting, or even looking, at a dog increases our levels of oxytocin.
“These dogs are turning us on by looking at us,” he said.
Our evolving closeness to dogs has implications for the laboratory, he noted, and perhaps all of society.
Serpell pointed to commentator Tucker Carlson’s recent statement that dogs are the social equals of humans, and that therefore Micheal Vick should have been executed for killing them.
“Lots of people feel the same way,” he said.
Posted by jwoestendiek January 13th, 2011 under Muttsblog.
Tags: beagle, caat, canines, center for alternatives to animal testing, cures, disease, dog, dog lovers, dogs, experiments, genes, genetics, humane, james serpell, johns hopkins university, laboratory, love, medcial, medical, opposition, oxytocin, pain, pavlov, products, research, rising, school, stature, status, stress, tests, therapy, treatment, university of pennsylvania, veterinary
Scientists have discovered a gene mutation that causes a fatal neurodegenerative disease in American Staffordshire terriers, and they say the same gene may also be linked to a fatal brain disease in humans.
The discovery of the gene may lead to improved screening and diagnosis of the disease in dogs, and could be a first step in developing a cure for NCLs (neuronal ceroid lipofuscinoses) in humans, Business Week reports.
NCLs are a family of diseases that lead to mental and motor deterioration and death.
Adult-onset NCL affects one of every 400 registered American Staffordshire terriers, according to research team member Dr. Natasha Olby, an associate professor of neurology at North Carolina State University.
Genetic analysis revealed the location of the specific gene and an entirely new mutation that has not been reported in people.
In humans, NCLs such as Batten disease mostly affect children, but there is an adult-onset form called Kufs’ disease that causes gradual death of brain neurons, resulting in vision loss, epilepsy, loss of coordination and dementia, according to the National Institute of Neurological Disorders and Stroke.
The findings mean that researchers can now conduct tests to determine if the same mutation is responsible for Kufs’ disease in humans.
Posted by jwoestendiek September 1st, 2010 under Muttsblog.
Tags: american staffordshire terrier, animals, batten disease, brain disease, diganosis, discovered, discovery, disease, dogs, gene, health, humans, kufs' disease, mutation, ncl, ncls, neurodegenerative, north carolina state university, pets, pit bulls, pitbulls, research, science