Two University of Washington scientists think it might be possible to slow the aging process in canines and are launching a pilot study with 30 dogs to see if the drug rapamycin significantly extends their lifespans.
The researchers, using $200,000 in seed money from the University of Washington, plan to use pets, not laboratory animals, for the initial study, and recruit volunteer dogs — or at least dogs whose owners volunteer them — for larger scale studies in the future.
Daniel Promislow, an evolutionary geneticist, and Matthew Kaeberlein, a molecular biologist, say the study is aimed at determining whether rapamycin could lead to longer lives for dogs — as studies have shown is the case when it’s used on yeast, fruit flies, worms and mice.
“We’re not talking about doubling the healthy life spans of pets,” said Kaeberlein. “But at a minimum I would predict that you would get a 10 to 15 percent increase in average life span, and I think bigger effects are possible.”
In the pilot study, 30 large, middle-aged dogs will be involved — half receiving low doses of rapamycin, half receiving placebos.
The researchers say that subsequent studies will seek to enroll pet dogs from across the country.
Kaeberlein and Promislow hosted a meeting in Seattle last week where experts from across the country discussed the drug rapamycin and its possible effects on the health and longevity of dogs, the Seattle Times reported.
Currently used along with other medications to prevent rejection in organ-transplant patients, rapamycin has been called a promising anti-aging drug — though there have been no studies involving humans.
But almost 50 laboratory studies have shown that the compound can delay the onset of some diseases and degenerative processes and restore vigor to elderly animals, extending life spans by 9 to 40 percent.
Rapamycin functions, in part, by inactivating a protein that promotes cell growth. As a result, cells grow more slowly, which retards the spread of cancer.
Promislow, who has two elderly dogs of his own, noted that even if the drug doesn’t increase the life span of dogs, it could serve to keep them healthy longer. “We’re trying to understand why some dogs age better than others, and help all dogs age in a better way,” he said.
The drug has been shown to have serious side effects, including poor wound healing and an increased risk of diabetes, when used at the high doses required for organ transplant patients.
But the low doses used in anti-aging research with mice and other lab animals cause few side effects.
There have been no large-scale human trials. Studying how the drug affects dogs — who suffer many of the same old-age ailments as their masters — makes it possible to explore the possible benefits of rapamycin both more quickly and at a lesser cost.
If it does turn out to be a sort of fountain of youth — for dogs, humans, or both — the potential profits would be enormous.
“I think it’s worth a go, not just from what it can teach us about humans, but for the sake of the animals themselves,” said University of Alabama Biology Department Chairman Steven Austad, an expert in aging research who is not involved in the project. “It may not work in dogs, but if it did, boy, it’s going to be huge.”
According to the Seattle Times article, drug companies aren’t very interested in rapamycin because it’s no longer under patent.
But the researchers are hoping dog lovers, dog-food companies and some foundations might be willing to contribute to further research.
They’ve set up a website, dogagingproject.com,where people can donate and sign their dogs up to take part in the research.
“Given how I feel about my pets, I see this as a unique project where there’s a real potential for citizen science,” Kaeberlein said. “I think it would be great if pet owners who are really interested in improving the health of their animals would help fund this work.”
(Photos: UW scientists Matt Kaeberlein, with his dog Dobby, and Dan Promislow, with his dog Frisbee; by Steve Ringman / The Seattle Times)
Posted by John Woestendiek November 4th, 2014 under Muttsblog.
Tags: animals, anti aging, anti aging drug, biology, cancer, cells, citizen science, compound, Daniel Promislow, death, dog, dogs, drug, drugs, extending, fountain of youth, funding, geneticist, health, ifespan, laboratory, life, lifespans, lives, longer, Matthew Kaeberlein, molecular, pets, rapamycin, research, sickness, study, university of washington
A golden retriever named Bretagne is all over the Internet today — today being 9/11 — looking much grayer around the muzzle than she did in 2001 and being described as the only search and rescue dog at the World Trade Center who is still living.
Whether that’s accurate depends on how you define “living.”
Not to pick nits, but there’s another dog, a German shepherd named Trakr — said by some to have found the last human survivor of the World Trade Center attack — who lives on … in a way.
Trakr was cloned in 2009, after his owner, a police officer turned actor, won an essay contest seeking the world’s most “cloneworthy” dog.
It’s a long story, one you can read about in the book, “DOG, INC.,” which recounts how dog cloning became a commercial enterprise.
Here’s the short version: Trakr was the partner of James Symington, a Halifax, Nova Scotia, police officer. When Trakr was retired, Symington claimed him as his own. On Sept. 11, 2001, after seeing news reports, Symington, without authorization from his department, took Trakr to the World Trade Center.
There, as Symington recounts it, Trakr discovered Genelle Guzman buried in the rubble — the last survivor found.
Others dispute his account.
Symington later moved to California to pursue a career in acting, taking Trakr with him. When an American company called BioArts announced it was holding a “Golden Clone Giveaway,” Symington submitted an essay, and won.
BioArts footed the bill (about $150,000) and sent samples of Trakr’s DNA to South Korean veterinarian Hwang Woo-Suk, who was on the team at Seoul National University that produced the world’s first canine clone, Snuppy. He’d since been fired and opened his own laboratory, Sooam Biotech Research Foundation.
Trakr’s DNA was inserted into five “surrogate” egg cells, each of which was zapped with electricity and implanted into a different female dog.
In June 2009 five clone puppies were born and, a few months later, delivered to Symington. He named them Trustt, Solace, Valor, Prodigy, and Deja Vu, and said he planned to train them all as search as rescue dogs who would carry on Trakr’s legacy.
They seem to have fallen out of the limelight since then, and their Facebook page hasn’t been updated for a couple of years.
Earlier this year, the man who pushed dog cloning and sponsored the “Golden Clone Giveaway,” in an apparent turnaround, said cloning dogs — a service still offered in South Korea — was not a viable, profitable, or humane pursuit, noting that it took up to 80 dogs to clone just one.
Lou Hawthorne headed BioArts, and spearheaded the earliest (unsuccessful) efforts to clone dog at Texas A&M University. That research was funded by University of Phoenix founder John Sperling, who died last month.
While some of the main characters involved in dog cloning seem to be fading from public view, from Trakr’s clones to Sperling, dog cloning is not — Sooam Biotech is still carrying out clonings for customers who want duplicates of their dead or dying pets, at a price that has dropped to about $100,000.
But back to the dog who is in the news — Bretagne. She returned this week to the site of the former World Trade Center complex with her longtime handler and owner, where they were interviewed by Tom Brokaw for NBC’s Today Show.
Bretagne (pronounced “Brittany”) is one of eight finalists for the American Humane Association’s annual Hero Dog Awards, and later this month she’ll travel with her owner to Beverly Hills for the awards ceremony.
My hunch, and hope, is that Bretagne is not destined to be cloned, and that her owner realizes what many customers of dog cloning have not — every dog, and every person, is one of a kind. And one of a kind means one of a kind. That special something inside your dog can’t be re-created in a laboratory.
Posted by John Woestendiek September 11th, 2014 under Muttsblog.
Tags: 9-11, 911, animals, bioarts, bretagne, cloned, clones, cloning, death, dog, dog cloning, dog inc., dogs, golden clone giveaway, james symington, laboratory, last, life, living, pets, re-creating, rescue, search, search and rescue, September 11, sooam, surviving, trakr, world trade center
You’d think Brian Andrews, as an investigative reporter at CBS News in Miami, would have plenty of legitimate and important issues to pursue — given all the land-raping, government corruption, injustice, drugs and sleaze the state of Florida has to offer.
Instead, he took his investigative skills inside a dog’s mouth. And he discovered there were germs in there.
News flash? Not exactly. We present it here not because it’s breaking news, but because it’s a good example of broken news — the kind of dopey reports that are increasingly common these days as TV news outfits, like newspapers, and websites, opt for quick and easy, crowd-scaring or crowd-pleasing, stories, then do their best to hype, tease and sensationalize them.
To determine whether you should let your dog lick your face, Andrews, a member of the station’s “special projects” team, gathered saliva samples from dogs in Fort Lauderdale and West Palm Beach and sent them to a lab to be tested, as part of the station’s continuing series called “How Dirty Is It?”
He was trying to determine if the adage nobody believes in the first place — the one about a dog’s mouth being a pristinely clean place — was really true.
We all know, or should, that there are going to be germs in a dog’s mouth, based simply on the sort of things that go in there. We also know, or should, that there are also plenty of germs in our own.
Upon completion of the doggy saliva tests, Nova Southeastern University microbiologist Dr. Julie Torruellas-Garcia concluded, “There was quite a bit of bacteria that grew from the dogs’ mouths.”
Based on the cultures grown in the lab from the samples, she said, there was “evidence of Nyceria, which is linked to STDs, pneumonia and plaque.”
“While our testing did not reveal the presence of any e-coli or bacteria that could cause a staph infection, Dr. Torruellas-Garcia and her students found globs of other microbes,” the news report said.
“You may want to think twice,” the report reads, “before you and your dog exchange siliva.” (We’re pretty sure they meant saliva.)
After raising fears about mouth to mouth contact with dogs, Andrews, in a complete turnaround, goes on to present a veterinarian who said kissing your dog isn’t all that dangerous. West Palm Beach Veterinarian Ken Simmons said any bacteria in a dog’s mouth doesn’t stay there for long.
“In the end, the testing didn’t reveal anything out of the ordinary,” the story reports.
So the point of it all was …?
Yes, the canine mouth, like the human mouth, is a breeding ground for germs. (Perhaps a more interesting story approach would have been if Andrews swabbed inside his own mouth, and compared the germs he might be carrying behind his own well-flossed grill with those of dogs.)
And, yes, dogs can pass on illnesses to us, and vice versa.
But spare us the scare tactics, news guys. Stop wasting our time by telling us the obvious, because, obviously, we already know that. And don’t bad-mouth dogs, no matter how bad their mouths are.
Posted by John Woestendiek May 15th, 2014 under Muttsblog, videos.
Tags: adage, bacteria, breaking news, brian andrews, broken news, dog, dogs, fear, germs, health, investigative, kiss, kisses, kissing, lab, laboratory, lick, licking, licks, manipulation, mouth, news, news media, reporter, reporting, saliva, scare tactics, special projects, television, tests, tv, zoonosis, zoonotic
With more than 500 canine clones now roaming the world, you wouldn’t think the fact that one has been produced for a pet owner in the UK would make such a big splash.
But it has, and a big splash is just what the cloners had in mind.
To introduce its unique service to Britain, Sooam Biotech, the South Korean laboratory that’s now the only company cloning dogs, borrowed from an earlier chapter in dog cloning’s bizarre history. It held a public contest, awarding a free cloning as the grand prize.
The winner: Rebecca Smith, 29, of London, who learned in late March that a clone of her 12-year-old dachshund Winnie had been born in a Seoul laboratory, BBC reported.
She named the dog Mini Winnie.
The competition saw dog owners submit videos of their dogs and compete for the chance to “immortalize” their pet for free. The bill for dog cloning normally runs around $100,000.
“Sooam Biotech is looking for one person with the most special and inspiring reason for cloning his/her beloved dog,” the company said in announcing the contest.
The contest was similar to one held in the U.S. when dog cloning first hit the market. It was called the “Golden Clone Giveaway,” and the winner was TrakR, a search and rescue dog whose owner said the German shepherd found the last survivor in the rubble of 9/11.
The weird and wacky story of how dog cloning was achieved, how it was marketed, and the first customers to sign up for it can be found in my book, “DOG, INC.: The Uncanny Inside Story of Cloning Man’s Best Friend.”
The UK’s first canine clone — who won’t arrive in the country until after a 6-month quarantine period — was cloned at Sooam Biotech, a laboratory run by Hwang Woo Suk, who was a member of the Seoul National University team that produced the world’s first canine clone, Snuppy, in 2005.
That research began after an earlier effort to clone a dog in the U.S., at Texas A&M University, was unsuccessful.
The Texas A&M research was funded by John Sperling, founder of the University of Phoenix. After cloning a cat, and assorted farm animals, the Texas A&M efforts to clone a dog were called off, but Sperling’s front man, who had established a company to store the cells of dead and dying dogs (Genetic Savings & Clone), even before dog cloning was achieved, later teamed up Hwang and Sooam to offer an online auction, with the highest bidders receiving clones of their dogs.
Hwang founded his lab after getting fired from Seoul National University when his claim to have produced the world’s first cloned human embryos was deemed fraudulent. He was later convicted of embezzling research funds and illegally buying human eggs, but his 18-month sentence was suspended.
Hwang has more recently has embarked on trying to clone a woolly mammoth from 10,00-year-old remains found frozen in Siberia.
Meanwhile, he’s churning out laboratory-created dogs, more than 500 of which have been born to surrogate mother dogs at his lab and kennel.
To create Mini Winnie, a piece of skin was taken from Winnie and transported to Seoul. Cells from the sample were placed inside an anonymous donor dog’s egg cell and, with a jolt of electricity, they merged.
Then the embryo was implanted inside a surrogate dog that gave birth, via Caesarean, to Winnie on March 30.
“The world would be a better place with more Winnies in it,” Smith, 29, says in a Channel 4 documentary, “The £60,000 Puppy: Cloning Man’s Best Friend.”
Smith received the original Winnie as a present on her 18th birthday, and she says the dog helped her overcome “lots of demons,” including an eating disorder. Smith says Mini Winnie looks identical to the original, who is old and arthritic, but still alive.
Hundreds of pet owners have had dogs cloned since the first customer, a California woman who received five copies of her dead pit bull, Booger.
Critics of the process say cloning doesn’t result in the resurrection of an animal, but a laboratory-made twin, whose creation requires the involvement of numerous other dogs, and who might not act like the original at all.
Initially, two South Korean companies were cloning dogs for pet owners (and even more for research purposes), but one of the, RNL Bio, has pulled out of the dog-cloning business.
While the cloning process has grown more efficient, some animal welfare groups say risks are still high.
Dr Katy Taylor, Head of Science at The British Union for the Abolition of Vivisection, said: “Cloning is a very unpredictable and extremely wasteful process … In order to produce just one ‘perfect’ clone, many puppies with the same genes as a loved animal will be born … Some of these puppies will be aborted or will die soon after birth from unpredictable health complications and severe birth defects.”
Defective pups, and the South Korean laboratory’s failure to follow animal welfare protocols, were among the reasons cited by the American company that teamed up with Hwang for pulling out of its dog cloning arrangement.
The documentary, while it mostly follows the judges as they visit with contestants and their dogs, does go some interesting places, including Edinburg, for an interview with Sir Ian Wilmut, cloner of Dolly the sheep. Wilmut doesn’t endorse pet cloning, and says he remains skeptical of it, saying it will lead to lots of disappointed customers who, despite their hopes, won’t get an animal with the same personality as the original.
There’s also an interview with a pet owner, not a contestant, who views dog cloning as a Hitleresque pursuit, and there are several allusions to the fact that some Koreans eat dog meat.
“The £60,000 Puppy: Cloning Man’s Best Friend” was made by the same independent production company that produced “I Cloned My Pet,” several episodes of which appeared on TLC.
“The £60,000 Puppy” is an improvement over those productions, which brushed aside most ethical questions and animal welfare concerns about pet cloning. While the new documentary doesn’t delve too deeply into them either, it does present something more than a one-sided view.
Like the earlier documentaries, it reinforces that most customers of dog cloning are, shall we say, eccentric sorts, and that their attachment to their dogs — as with all of us — is a powerful one.
Perhaps the most telling moment, though, comes as the judges debate — American Idol style — the public relations benefits of each contestant.
After that, the winner is … after a long, long pause … announced.
Cloning, it seems, is no longer some futuristic pipedream. It has become a reality, and apparently an entertainment form.
My view? Cloning is no game show, or at least it shouldn’t be.
(Photos: Top, Mini Winnie / Channel 4; middle, Hwang in his lab / John Woestendiek; bottom; Smith and the original Winnie / Channel 4)
Posted by John Woestendiek April 11th, 2014 under Muttsblog.
Tags: animals, biotech, book, canine, cells, clone, cloned, clones, cloning, contest, customers, dog cloning, dog cloning book, dog inc., dogs, free cloning, great britain, hwang woo suk, laboratory, marketing, pets, science, seoul, seoul national university, snuppy, sooam, technology, uk
Boulder City Councilwoman Mary Young wants to know how feasible it would be to require DNA samples from dogs, and create a registry so that, through DNA analysis, poop left on city trails could be traced to dog owners.
She’s not suggesting every dog in Boulder be tested (yet) — just the estimated 35,000 with so-called “green tags” that allow them to romp off-leash on some of the city’s trails and greenspaces.
Young has asked that the issue be discussed at tonight’s City Council meeting, the Boulder Daily Camera reports. (Yes, it happens to be an April Fools Day meeting, but nobody’s joking here.)
I would hope Boulder looks not just at whether it can be done (it can), but at whether it should be — that city leaders consider, in addition to the price tag of such a venture, the ethics and implications and utter goofiness of it.
There’s a lot of dog-related technology I don’t like (click the banner at the top of this page for one example) and poop-detection technology is near the top of the list.
Not just because of its Orwellian overtones, not just because it’s heavy-handed, dictatorial, silly, creepy, intrusive and expensive. It’s also because technology, unleashed, has a habit of oozing beyond the boundaries of its originally intended purpose — DNA-testing of dog poop being just such a case — and spreading into ever scarier realms.
The day could still come when your tossed cigarette butt, un-recycled soda can or expectorated phlegm could be traced back to you, which, come to think of it, might be a better use of DNA technology than that being offered by the dog poop sleuths.
Declaring war on poop, and bringing out technology’s big guns, is overkill. Especially when the real solution can be achieved by simply bending over and picking up what your dog leaves behind.
In case you haven’t been following our posts on this issue, here’s how it works:
Deciding unscooped dog poop is simply intolerable, homeowners associations, apartment complexes or government entities sign up with a company called PooPrints, which sends them the supplies needed for residents to take swabs from the cheeks of their dogs. Those are sent to Tennessee, and a doggie DNA registry is created.
After that, any pile of poop that is found can be gathered, packaged and sent to a lab in Tennessee, where it can be unpackaged and tested and, by comparing DNA markers, matched to an individual dog, assuming that dog’s DNA is in the registry.
The company lets management know who the poopetrator was, and the owner is fined $100 or so — or, if a repeat offender, perhaps told they and/or their dog should move somewhere else. Thereby a community is made safe from scofflaws, as well as, say, a grandmother whose back might have been hurting too much one day to pick up every last dropping left by her Shih Tzu.
Here in my current home state, North Carolina, apartment complexes in Winston-Salem and Wilmington are among the growing number of property management companies and government entities turning to PooPrints.
Yes, dog poop can be hazardous to our health, and harmful to the environment.
So can the feces of all the non-domesticated animals we live among, but don’t feel compelled to prosecute for pooping.
So, too, can the dumpage of corporate entities, like the thousands of tons of coal ash spilled into the Dan River by Duke Energy, coating 70 miles of the river with toxic sludge.
That’s a little harder to pick up after, and, I’d suggest, at least as deserving of society’s consternation and oversight and vigilance as dog poop — even if punishing the culprit won’t make them change their ways. (Big companies, unlike the average dog owner, can hire lawyers to avoid fines, and, if unsuccessful, they just pass the costs along to their customers.)
Finding clean sources of energy — that’s a use of technology I like. Using DNA to solve murders (and clear the wrongly convicted) seems a good use, too.
But gathering, packaging and mailing dog poop so technicians in Tennessee can comb through it and test it, by comparison, seems a silly use of our technological muscles.
In Colorado, Boulder officials say dog waste on public trails is one of the most common complaints the city receives, so it’s not surprising that they’d turn to a company that claims to have the solution.
Eric Mayer, director of business development for BioPet Vet Lab in Knoxville, Tenn., said the company’s PooPrint service is used by private property management companies in 45 states and in Canada. Franchises are popping up all over, like Burger Kings.
So far, the company doesn’t have contracts with any municipalities, but officials have been in talks with a half dozen different local governments. He said he expects to sign the first municipal PooPrints contract with Ipswich, Mass., sometime this year.
Maybe, if poop detection continues to catch on, it would be good for the economy. Maybe, you too could have a fulfilling career as a dog poop laboratory technician.
But there are far better ways to spend our time and money, and far bigger problems more deserving of our rage. Between all the emotion, and all the technology, we seem to forget that we can simply …
Pick it up!
(Top photo, fake poop question mark, from Big Mouth Toys; bottom photo, sludge from the Dan River spill, courtesy of Dan River Basin Association)
Posted by John Woestendiek April 1st, 2014 under Muttsblog.
Tags: amok, animals, apartments, biopet, boulder, clean, coal ash, colorado, communities, dan river, detection, dna, dog, dog owners, dog related technology, dogs, duke energy, dump, dumping, enforcement, ethics, feces, fine, franchises, genetics, identify, laboratory, markers, north carolina, owners, pets, poop, pooprints, questions, registry, responsibility, samples, scoop, shit, spill, swabs, technology, waste, wilmington, winston-salem
I’m a big fan of dogs, and not a fan of dentistry at all, so as you might expect I’ve got some problems with dogs being used to test out dental implants, in hopes of making better and safer ones for humans.
Especially considering that dogs are suffering and dying in the process, as The Humane Society of the United States says is the case at Georgia Regents University.
The HSUS last week released this report, containing undercover footage obtained during its three-month-long investigation at GRU. The experiments lead to two questions in my mind.
First, since the research is supposed to benefit humans, why not use humans for the tests? I’m sure there are plenty of people who are in need of dental implants and who, unable to afford them, might be willing to volunteer. I myself might take the risk, assuming that the researchers don’t insist on killing me afterwards to get a sample of my jawbone.
And that’s question number two: Why is it necessary to kill a dog after he’s already made an unwilling contribution to science — or at least a contribution to us humans being able to have gap-free permanent false teeth and not having to mess with things like denture adhesives?
As one dentist told the Humane Society, it’s not.
“In the two studies I reviewed, human research subjects could have been used, given that the products were already approved by the Food and Drug Administration and bone biopsies are commonly done in human studies,” said James P. Jensvold, DDS.
“Animals used in research are often ‘sacrificed’ at the end of the study, and this is accepted as standard practice without taking into consideration the unnecessary emotional and physical suffering that the animals must endure,” Jensvold added. “As a dental student and oral and maxillofacial surgery resident, I witnessed laboratory animals being treated as little different than a test tube, which is inconsistent with the values of compassionate healthcare.”
“Dogs don’t need to die for frivolous dental experiments,” said Wayne Pacelle, HSUS president and CEO. “It’s painful to watch these forlorn dogs sacrificed for these questionable purposes…”
If you tend to distrust dentists, and Wayne Pacelle, perhaps you’ll believe actress Kim Basinger, who narrates the HSUS report:
“GRU buys dogs from a Class B dealer who’s under federal investigation,” she notes. “Dogs like Shy Guy, along with others, who may have been famiily pets, were all used for unnecessary dental experiments. Their teeth were pulled out and replaced. It’s very painful, just look into their eyes.”
(Dogs used in the experiments, after having their teeth removed, are given a canine version of dental implants, not human ones, like you find in those freakish — to me, anyway — ads for Pedigree Dentastix.)
The HSUS investigator witnessed dogs having their teeth pulled out and replaced with implants. Once the experiments were over, the dogs were euthanized for a small sample of their jaw bone. GRU has been conducting dental implant research on random-source Class B dogs for years.
There are only six random-source Class B Dealers still active in the U.S. They are permitted to gather dogs and cats from various sources, including auctions, “free to good home” ads, online sources, flea markets, and even animal control and some shelter facilities — and resell them to research facilities. There have been cases of stolen pets ending up in research laboratories via ClassB dealers, the HSUS says.
The dealer who sold the dogs to GRU, Kenneth Schroeder, has previously been charged by the U.S. Department of Agriculture with violations of the Animal Welfare Act, including obtaining dogs from unauthorized sources, according to the HSUS.
Dr. Mark Hamrick, Senior Vice President for Research at Georgia Regents University, issued the school’s response to the HSUS allegations:
“As an institution, we are committed to research that will provide a direct benefit to patient lives by restoring function to damaged and diseased organs and tissues … The Food and Drug Administration, which provides oversight for medical device safety and procedures including dental implants, requires preclinical studies in animals demonstrating that the device or procedure is both safe and effective for its intended use in humans … The research being done with dogs is neither frivolous nor unnecessary, as alleged by the investigation, and is performed in order to develop safe, effective dental procedures for people.”
The HSUS says the studies are being done at the university in part to compare a dental implant invented by researchers at GRU, in conjunction with a private company, with that of a competitor.
According to the HSUS, 65,000 dogs per year are used for research, testing, and education in the U.S.
Posted by John Woestendiek November 25th, 2013 under Muttsblog, videos.
Tags: animal welfare, animals, class b, dealers, dental, dentist, dentistry, dogs, experiments, georgia regents university, gru, humane society of the united states, humans, implants, investigation, kim basinger, laboratory, medicine, pets, random source, science, teeth, tests, undercover, video
It’s the one-year anniversary for 120 beagles who, around this time last year, learned the true meaning of independence.
Up until then, even here in the land of the free, they weren’t.
Instead, like thousands of other beagles bred and born for the sole purpose of laboratory use, they’d never experienced what most dogs take for granted — things like grass and dirt and running — and were destined, once their use in testing was complete, for something quite contrary to a loving home.
The beagles had been left locked in a research facility operated by Aniclin Preclinical Services in Warren County, N.J. after its parent pharmaceutical company went bankrupt. When their situation came to light, a judge order the dogs turned over to rescue groups.
One year ago, a group of them were welcomed to Pets Alive Animal Sanctuary in New York, where work began on socializing them so they could be adopted out as family pets.
This coming Sunday, some of them will gather for a reunion.
About 35 of the adopters stay in touch on Facebook, offering support and following each others progress through photos and stories.
They — and any of the others who adopted a “freegle,” as they are prone to calling the dogs rescued from the laboratory — are gathering July 10, from 12:30 to 4 p.m., at Kennedy Dells Park, 355 North Main Street in New City, New York.
Among those attending will be a beagle named Grace, who has her own Facebook page, called Saving Grace. Grace’s owner said that while word of the reunion has gotten out among those who stay in touch, other beagles adopted from the group are also invited, as well as everyone else who participated in rescuing them.
Shelters, sanctuaries, volunteers and staff are “most welcome to attend and meet the families and hear the stories of how the Freegles have been adjusting to the good life.”
(For questions or to RSVP, send an email to firstname.lastname@example.org.)
I met several lab beagles while researching my book — including some flourescent beagle clones in South Korea. In Texas, I interviewed the woman who cared for the beagles used in attempting to clone a dog at Texas A&M University.
Jessica Harrison, a graduate student at the time, was in charge of socializing the beagles and finding adoptive homes for them — not usually the case or fate of laboratory beagles — after their services in the lab were no longer required.
“What they teach them is to be still,” she told me. “As puppies, they teach them to just freeze when a person messes with them. We had to kindo of undo that and say, ‘No,we want you to move around and be excited.’
“We slowly exposed them to all the things they’d be exposed to in a family home — like TVs, mirrors, grass, trees, flowers, birds and bees. These dogs had never seen any of that. You put them down on the grass, and they’re like, ‘What’s this?’ It was kind of overwheliming. You get used to it, but at first it’s like, these are dogs, how can they not know these things?”
The use of dogs in laboratory research was declining, but it has jumped up in recent years, with much of the increase due to advancements in, and the promise of, gene therapy.
(Photos: Top photo from the Facebook page of Freegles Justice and Skipper; bottom photo by John Woestendiek)
Posted by John Woestendiek July 4th, 2011 under Muttsblog.
Tags: adopt, adopted, aniclin, animal sanctuary, beagles, best freinds, cloning, dog inc., dogs, experiments, flourescent, freed, freegle reunion, freegles, kennedy dells park, lab animals, lab beagles, laboratory, medical, new city, new jersey, new york, pets, pets alive, pharmaceuticals, rescue, research, reunion, sanctuary, science, shelter, warren county