A new medication that claims to soothe dogs who are frightened by loud noises, such as fireworks and thunderstorms, will be available to veterinarians in the U.S. within a week — in plenty of time to help make the 4th of July less traumatic.
Sileo (not a very serious sounding name, is it?) comes in a gel form and is the first prescription medicine for treating anxiety over loud noises in canines– a widespread problem that leads to property destruction, running away and life-threatening injuries.
Its U.S. maker, Zoetis of Florham Park, New Jersey, says Sileo (pronounced SILL-lee-oh) works by blocking norepinephrine, a brain chemical similar to adrenaline that pumps up anxiety.
It is applied to a dog’s gums via a pre-filled, needle-less syringe.
Zoetis says the medication will give owners of the estimated third of the 70 million dogs in the U.S. who have problems with loud noises an alternative to human anti-anxiety pills, like Xanax, that sedate dogs for many hours.
Sileo takes effect within 30 minutes to an hour.
The pre-filled applicator costs $30, and contains enough for two doses for a dog of 80 to 100 pounds, four doses for a 40-pound dog, or six doses for a small dog.
Dogs can be re-dosed every two hours, up to five times during each noise event, Zoetis said in a press release.
Zoetis has exclusive rights to distribute Sileo in the U.S. under an agreement with the medication’s developer, Orion Corp. of Finland.
In testing on 182 pet beagles conducted on New Year’s Eve, 75 percent of their owners rated its effect good or excellent. Side effects were rare and minor, the company says.
(Photo: Provided by Zoetis)
Posted by John Woestendiek May 17th, 2016 under Muttsblog.
Tags: 4th of July, animals, anxiety, behavior, canine, dog, dogs, drugs, fear, fireworks, first, fourth of july, gel, july 4, loud, medication, medicine, new years, noise, noises, pets, prescription, sileo, syringe, thunderstorms, veterinarian, veterinary, zoetis
Time was of the essence after a Massachusetts dog consumed three wristwatches — almost in their entirety.
The owners of Mocha said they rushed the dog to MSPCA’s Angell Animal Medical Center in Boston after finding a few remaining pieces of the watches — which had been inside a drawer the dog somehow opened — on the floor.
Mocha was admitted on April 16, the hospital said in a press release, and endured a three-hour endoscopic procedure which allowed the medical team to determine how much material was in her belly — and the best way to remove it.
The team was able to remove some of the leather from Mocha’s stomach using the endoscopy instruments.
As for the rest, they decided to let nature take its course, which nature did.
Over a period of several days, Mocha eliminated another pound of broken leather straps, buckles and various other metal pieces, said Dr. Zachary Crouse.
“We were especially cautious and wanted to avoid surgery—given her history,” he said.
Mocha was admitted to the animal hospital in August of 2014 after swallowing a plastic juice container lid. It obstructed her intestine and had to be surgically removed.
Angell doctors credited the quick thinking of Mocha’s owners, Michele Parkinson and Jeff Courcelle of Salem, who rushed the dog to the animal ER immediately after discovering bits and pieces of the watches on the floor of their home.
“Mocha dodged a bullet for sure and I credit her owners for getting her straight to the hospital,” said Dr. Crouse. “This could easily have turned into a life-threatening situation if they had delayed.”
“We brought her to Angell as soon as my husband saw the broken watch pieces, even though she was showing no symptoms whatsoever,” said Parkinson, who works as a nurse in the hematology department of a major area hospital.
Mocha stayed at the medical center for two days, and returned last Monday for a follow-up exam. An x-ray showed that six small pieces remain inside her, but should pass without surgical intervention.
“One thing’s for sure: we’re going to do everything we can to keep anything remotely ingestible out of her reach,” said Parkinson.
(Photos: Angell Animal Medical Center)
Posted by John Woestendiek April 27th, 2015 under Muttsblog.
Tags: angell, angell animal medical center, animals, ate, boston, consumed, doberman, dog, dogs, health, medicine, mocha, mspca, pets, safety, salem, surgery, swallowed, veterinary, watch, watches, wristwatch
Buttercup can thank dog for being alive.
The Key West cat received a blood transfusion from a dog last month — not an unknown procedure, but a pretty rare one.
It’s called xenotransfusion, and according to the U.S. National Library of Medicine only 62 cats have been known to undergo the procedure.
On Sept. 16, Dr. Sean Perry from the Marathon Veterinary Hospital pumped the blood of a greyhound into an orange tabby, in hopes of increasing the cat’s red blood cell count.
Veterinarians decided to use dog blood they had on hand after learning that suitable cat blood could take weeks to receive.
“It’s a situation where you can’t give type A blood to a type B blood cat because it’ll cause a severe immune reaction,” Perry said. “It was actually safer to give the cat dog’s blood.”
Buttercup’s owner, Ernie Saunders, brought the cat to the vet after it became lethargic, ABC reported.
After a few tests, veterinarians learned Buttercup’s red blood cell count was down to 7 percent. Cats should have a red blood cell count of at least 35 percent, Perry said.
“Cat’s blood is a little harder to come by and not as available as dog’s blood,” Perry said. “We had greyhound blood packs that we get from a blood bank that has red blood cells separated from plasma. Buttercup showed no signs of rejection during the transfusion.”
Perry said as far as veterinarians know, cats are the only animal that accept transfused blood from dogs, and that after it is done once it can’t be done again.
Since the procedure, Saunders said Buttercup has been more active.
In addition to learning about xenotransfusion, Saunders learned something else from the vet visit.
Buttercup, who he thought was a female, is a male.
Posted by John Woestendiek October 15th, 2014 under Muttsblog.
Tags: animals, blood, buttercup, cat, cat blood, dog, dog blood, florida, health, key west, marathon, medicine, pets, transfusion, veterinary, xenotransfusion
I’m a big fan of dogs, and not a fan of dentistry at all, so as you might expect I’ve got some problems with dogs being used to test out dental implants, in hopes of making better and safer ones for humans.
Especially considering that dogs are suffering and dying in the process, as The Humane Society of the United States says is the case at Georgia Regents University.
The HSUS last week released this report, containing undercover footage obtained during its three-month-long investigation at GRU. The experiments lead to two questions in my mind.
First, since the research is supposed to benefit humans, why not use humans for the tests? I’m sure there are plenty of people who are in need of dental implants and who, unable to afford them, might be willing to volunteer. I myself might take the risk, assuming that the researchers don’t insist on killing me afterwards to get a sample of my jawbone.
And that’s question number two: Why is it necessary to kill a dog after he’s already made an unwilling contribution to science — or at least a contribution to us humans being able to have gap-free permanent false teeth and not having to mess with things like denture adhesives?
As one dentist told the Humane Society, it’s not.
“In the two studies I reviewed, human research subjects could have been used, given that the products were already approved by the Food and Drug Administration and bone biopsies are commonly done in human studies,” said James P. Jensvold, DDS.
“Animals used in research are often ‘sacrificed’ at the end of the study, and this is accepted as standard practice without taking into consideration the unnecessary emotional and physical suffering that the animals must endure,” Jensvold added. “As a dental student and oral and maxillofacial surgery resident, I witnessed laboratory animals being treated as little different than a test tube, which is inconsistent with the values of compassionate healthcare.”
“Dogs don’t need to die for frivolous dental experiments,” said Wayne Pacelle, HSUS president and CEO. “It’s painful to watch these forlorn dogs sacrificed for these questionable purposes…”
If you tend to distrust dentists, and Wayne Pacelle, perhaps you’ll believe actress Kim Basinger, who narrates the HSUS report:
“GRU buys dogs from a Class B dealer who’s under federal investigation,” she notes. “Dogs like Shy Guy, along with others, who may have been famiily pets, were all used for unnecessary dental experiments. Their teeth were pulled out and replaced. It’s very painful, just look into their eyes.”
(Dogs used in the experiments, after having their teeth removed, are given a canine version of dental implants, not human ones, like you find in those freakish — to me, anyway — ads for Pedigree Dentastix.)
The HSUS investigator witnessed dogs having their teeth pulled out and replaced with implants. Once the experiments were over, the dogs were euthanized for a small sample of their jaw bone. GRU has been conducting dental implant research on random-source Class B dogs for years.
There are only six random-source Class B Dealers still active in the U.S. They are permitted to gather dogs and cats from various sources, including auctions, “free to good home” ads, online sources, flea markets, and even animal control and some shelter facilities — and resell them to research facilities. There have been cases of stolen pets ending up in research laboratories via ClassB dealers, the HSUS says.
The dealer who sold the dogs to GRU, Kenneth Schroeder, has previously been charged by the U.S. Department of Agriculture with violations of the Animal Welfare Act, including obtaining dogs from unauthorized sources, according to the HSUS.
Dr. Mark Hamrick, Senior Vice President for Research at Georgia Regents University, issued the school’s response to the HSUS allegations:
“As an institution, we are committed to research that will provide a direct benefit to patient lives by restoring function to damaged and diseased organs and tissues … The Food and Drug Administration, which provides oversight for medical device safety and procedures including dental implants, requires preclinical studies in animals demonstrating that the device or procedure is both safe and effective for its intended use in humans … The research being done with dogs is neither frivolous nor unnecessary, as alleged by the investigation, and is performed in order to develop safe, effective dental procedures for people.”
The HSUS says the studies are being done at the university in part to compare a dental implant invented by researchers at GRU, in conjunction with a private company, with that of a competitor.
According to the HSUS, 65,000 dogs per year are used for research, testing, and education in the U.S.
Posted by John Woestendiek November 25th, 2013 under Muttsblog, videos.
Tags: animal welfare, animals, class b, dealers, dental, dentist, dentistry, dogs, experiments, georgia regents university, gru, humane society of the united states, humans, implants, investigation, kim basinger, laboratory, medicine, pets, random source, science, teeth, tests, undercover, video
Suddenly the shih tzu began going in circles, nudged her in the left breast, then got down on the floor and howled.
It was unusual in several ways. For one thing, Taffy never barked.
Granato, as the dog continued yapping, reached for the spot Taffy had nudged and found a lump.
She visited doctors, had some tests done, and was told she had nothing to be concerned about. To be safe though, she underwent a biopsy. It confirmed what she suspected Taffy was trying to tell her — she had breast cancer.
“I did listen to the dog, but I also listened to me,” she told the South Jersey Times.
The ability of dogs to detect cancer is well documented, if not completely understood. But it’s unusual for one who hasn’t been trained to do so to make what seems to be a diagnosis.
Researchers believe what dogs are smellling are the chemical changes that occur when normal cells are altered by cancerous ones.
Granato found out she was in the first stage of breast cancer. Doctors removed the lump and she underwent chemotherapy. During her treatments, Taffy provided some emotional support, she said.
Granato said she has been in remission for four years. Doctors detected another lump last September, but she says she wasn’t too worried.
“I kept saying, ‘The dog didn’t bark,’ ” Granato said. “It can’t be.”
Results showed the lump was benign.
(Photo: Nancy Granato and granddaughter’s dog, Taffy; by Lori M. Nichols / South Jersey Times)
Posted by John Woestendiek October 9th, 2013 under Muttsblog.
Tags: animals, biopsy, breast cancer, cancer, detection, detects, dogs, health, lump, medicine, new jersey, pets, pitman, scents, shih-tzu, sniff
The disease is common in pigs but has only recently been diagnosed in dogs.
Eight dogs from the Canton area to the Cincinnati area, have fallen ill with similar symptoms over the past three weeks.
Of those, four died, according to the Cleveland Plain Dealer.
On Friday, one of those cases was confirmed as circovirus, said Department of Agriculture spokeswoman Erica Hawkins.
Testing continues on samples from the other seven dogs, and it’s too early to know if they all contracted the same disease, she added.
Pathologists sent samples from dogs to a lab at the University of California-Davis to test them for circovirus. A one-year-old beagle with circovirus died in California in the spring, and the school’s lab has the equipment to test for the virus. A study detailing the California case was released in April in the Centers for Disease Control’s online journal “Emerging Infectious Diseases.”
Symptoms of the virus included vasculitis (a destruction of the body’s blood vessels), severe vomiting, bloody diarrhea, fluid buildup around the lungs, as well as rapid heart rate and weakness.
In August, the state Department of Agriculture issued an alert after several dog deaths were reported in Norwood, just north of Cincinnati. Four dogs became sick with similar symptoms, and three of them died. All of the dogs had spent time at the same boarding kennel. The facility shut down temporarily and replaced its flooring and other equipment. But owners of the company say that was done as a precaution and that tests of the facility’s food, water and surfaces show no signs of anything that could have triggered the illnesses.
The other four suspected cases were all in the Akron area, but there are no indications that the dogs had spent time together.
Dr. Melanie Butera, a veterinarian at Elm Ridge Animal Hospital in Canal Fulton, treated all four of the Akron-area dogs. All became very ill with similar symptoms, and all were around 3 or four years old. One of the four died.
Health officials and veterinarians said that owners who suspect their dog has the illness should get the pet to a veterinarian right away.
Butera warned dog owners not to panic. There have only been a handful of cases so far, and even if circovirus is responsible for all the cases, it’s not the first time dogs have faced a new illness.
“Viruses mutate all the time, and we see that in human viruses, and sometimes mutations allow the virus to cross into a different species,” she said.
Posted by John Woestendiek September 10th, 2013 under Muttsblog.
Tags: animals, beagle, california, canal fulton, canine, Canton, cincinatti, circovirus, disease, dog, dogs, health, ill, medicine, norwood, ohio, pathology, pets, pig, porcine, sick, symptoms, uc davis, university of california, veterinarian, veterinary, virus
With all the research into how the medical issues of dogs often run parallel to our own, it’s no surprise that eight obsessive-compulsive Doberman pinschers are adding to our body of knowledge about that disorder.
A new study made use of MRI brain scans and found dogs and people with obsessive compulsive disorder (OCD) have similar brain abnormalities and share certain brain characteristics.
Three years ago, researchers found the shared gene believed responsible for flank-sucking, blanket-sucking and other compulsive behavior in Dobermans.
The new study shows what’s going on in their brains is similar — at least as an MRI sees it — to what’s going on in our’s.
“We have a lot of commonality with our best friend the dog,” said study leader Niwako Ogata, an assistant professor of animal behavior at Purdue University College of Veterinary Medicine in Indiana.
Just as elderly dogs with the canine equivalent of Alzheimer’s are being used as models to understand the degenerative disease in people, studying dogs is providing some clues into OCD, an anxiety disorder afflicting anywhere from 2 to 8 percent of Americans.
For the study, Ogata and colleagues recruited eight Doberman pinschers with CCD (canine compulsive disorder) and a control group of eight Dobermans without CCD, according to National Geographic. The team obtained MRI scans for each group and discovered that the CCD dogs had higher total brain and gray matter volumes and lower gray matter densities in certain parts of the brain. That’s similar to the structures of people brains’ with OCD.
It’s not known why both species’ brains show these features, Ogata said, but her team plans to repeat the experiment with more dogs and more breeds.
The team chose Dobermans because of the prevalence of CCD in the breed. About 28 percent of Dobermans in the U.S. are afflicted.
People with OCD often perform the same rituals over and over again, like washing and rewashing their hands and locking and relocking doors. In dogs, common compulsive behaviors include paw-licking and tail-chasing.
Ogata, whose study was published online in April in the journal Progress in Neuro-Psychopharmacology & Biological Psychiatry, said the study provides a better idea of “”how brains develop, and when and how genes interact with [their] environment to cause some behavior problems for both humans and dogs.”
Posted by John Woestendiek June 14th, 2013 under Muttsblog.
Tags: animals, behavior, blanket, brain, ccd, compulsive, disorder, doberman, dog, dogs, flank, gene, genetics, health, humans, licking, medicine, mri, Niwako Ogata, obsessive, ocd, pets, pinschers, purdue, research, science, species spanning, study, tail chasing, veterinary, zoobiquity